Obesity is already developing in early childhood between the age of three to six. Although most obesity associated diseases are diagnosed only in adulthood, they start unnoticed in childhood. Even in children this can lead to health affections such as high blood pressure, insulin resistance, and inflammation symptoms. In this area of research scientists look into the alterations and dysfunctions of adipose tissue in overweight children, which contribute to the development of sequelae. Samples of adipose tissue of children of different age groups are being scrutinized. With these clinical studies the correlation to the emergence of metabolic and cardiovascular diseases is being investigated. Attention is being especially given to adipokines as possible transmitters within this correlation. Furthermore, new prevention approaches are being drafted, which take into account the particular situation of childhood and of environmental factors, that have an impact on the development of adiposity.